Publications

Publications

Wantuch, P.L.; Knoot, C.J.; Robinson, L.S.; Vinogradov, E.; Scott, N.E.; Harding, C.M.; Rosen, D.A. A heptavalent O-antigen bioconjugate vaccine exhibits differential functional antibody responses against diverse Klebsiella pneumoniae isolates. Journal of Infectious Disease 2024, DOI: 10.1093/infdis/jiae097.

Wantuch, P.L.; Knoot, C.J.; Robinson, L.S.; Vinogradov, E.; Scott, N.E.; Harding, C.M.; Rosen, D.A. Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae. PLoS Pathogens 2023, 19:e1011367.

Knoot, C.J.; Wantuch, P.L.; Robinson, L.S.; Rosen, D.A; Scott, N.E.; Harding, C.M. Discovery and characterization of a new class of O-linking oligosaccharyltransferases from the Moraxellaceae family. Glycobiology 2023, 33:57-74.

Aceil, J.; Paschall, A.V.; Knoot, C.J.; Robinson, L.S.; Scott, N.E.; Feldman, M.F.; Harding, C.M; Avci, F.Y. Immunogenicity and protective efficacy of a prototype pneumococcal bioconjugate vaccine. Vaccine 2022, 40:6107-6113.

Duke, J. A.;  Paschall, A. V.;  Robinson, L. S.;  Knoot, C. J.;  Vinogradov, E.;  Scott, N. E.;  Feldman, M. F.;  Avci, F. Y.; Harding, C. M., Development and Immunogenicity of a Prototype Multivalent Group B Streptococcus Bioconjugate Vaccine. ACS Infect Dis 2021, 7 (11), 3111-3123.

Knoot, C. J.;  Robinson, L. S.; Harding, C. M., A minimal sequon sufficient for O-linked glycosylation by the versatile oligosaccharyltransferase PglS. Glycobiology 2021, 31 (9), 1192-1203.

Feldman, M. F.;  Mayer Bridwell, A. E.;  Scott, N. E.;  Vinogradov, E.;  McKee, S. R.;  Chavez, S. M.;  Twentyman, J.;  Stallings, C. L.;  Rosen, D. A.; Harding, C. M., A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae. Proc Natl Acad Sci U S A 2019, 116 (37), 18655-18663.

Harding, C. M.; Feldman, M. F., Glycoengineering bioconjugate vaccines, therapeutics, and diagnostics in E. coli. Glycobiology 2019, 29 (7), 519-529.

Harding, C. M.;  Nasr, M. A.;  Scott, N. E.;  Goyette-Desjardins, G.;  Nothaft, H.;  Mayer, A. E.;  Chavez, S. M.;  Huynh, J. P.;  Kinsella, R. L.;  Szymanski, C. M.;  Stallings, C. L.;  Segura, M.; Feldman, M. F., A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host. Nat Commun 2019, 10 (1), 891.